Translational neuro-imaging

Translational Neuroimaging Group
Klinik und Poliklinik für Epileptologie
PD Dr. med. Theodor Rüber

We are a young scientist group at the Department of Epileptology at the University of Bonn Medical Center. The group is composed of young researchers with backgrounds in medicine, neuroscience, computer engineering, physics, mathematics, and philosophy. Within a network of established scientists, the Translational Neuroimaging Group co-develops and applies cutting-edge neuroimaging methods to enhance understanding and diagnostics of neurological diseases, whereby focusing on epilepsy.

Methodologically, the Translational Neuroimaging Group bridges the gap between patient care and computational neuroscience. We work in close cooperation with the Department of Epileptology at Bonn University Hospital and perform structural and functional imaging using 3T MRI for the diagnosis of epilepsy patients. Besides the cooperation with the Clinic for Epileptology, we also process images from nuclear medicine (e.g. SPECT, Single-Photon Emission CT). 


Seizure imaging – post-hoc visualization of microstructural processes anatomically and temporally related to individual seizures, such as peri-ictal blood-brain barrier dysfunction or postictal hypoperfusion. © Theodor Rüber


  • Quantitative MR imaging
  • Functional MRI 
  • ASL (arterial spin labeling)
  • QSM (quantitative susceptibility mapping) 
  • Generative adversarial networks
  • Convolutional neural networks
  • Voxel-based morphometry (VBM)
  • Volumetric and surface-based analyses